It was about this checkboxes in the glade panel. Jog inhibit is essential for me, to prevent accidentally keyboard jog. Depending on clamping chuck or a-axis, i need to probe tool and z-offset at different positions.
The initial idea was, to have the boxes checked as default on start. I removed them from the inivars string, then they stayed unchecked. So i changed back to restore last state on start, and got used to it already, and i added leds to visualize more clearly.