Help to understand axes directions

Depends on how you look at it, i did read Aciera's post and went back to read mine as i though i messed up, but it is OK, i am talking about homing direction, he is talking about motion direction.
I'll try to explain, hopefully i do not make a bigger mess:
Look at it as the table is not moving but the head is moving, then translate that to table motion.
Does this make things easier or worse? I would like to know, thank you.

Okay, thats why they were opposite, homing vs traveling direction, as I believe, I guess I'm missing some very basic concepts here.

I`m trying to understand how my machine should be set for home.
The travels are X 1000 mm, Y 450 mm and Z 400 mm.

How should I set the homing to be as trivial and safe as possible?
I thought as my first post:
I'm setting my home positions and to order to:
1st: Z all the way down, nearest to the floor at value 0.0
2nd: X all the way to the left, nearest the lathe at value 0.0
3rd: Y all the way back, nearest to the wall at value 0.0

Should I set 0 values for all axes? This would make my machine runs on negative coordinates all the time, right? What would be typical for a machine like this?

I really appreciate your help, guys.

Homing defines your absolute zero position (ie G53), whenever you actually cut a part you will be using a work coordinate system (ie G54 ... G59) that is set to a corner of your machine vise or the part to be machined.

Thanks guys, wrapped my head around but if worked!