Except for versa probe and basic probe, the short answer is no general way to customize widgets.
Versa probe and basic probe look for customized ui and handler files.
This describes the process for them:
linuxcnc.org/docs/devel/html/gui/qtdrago..._probe_screen_widget
You can always add your own widget to qtdesigner.
the plugin link should be in a hidden file in your home folder:
.designer/plugins/python/Link to qtvcp_plugin.py
you could add more links, but it's a fair amount of work.
What widgets do you wish to customize?