help with disableing IRQ coalescing for Intel ethernet

I'm converting a PM-833TV mill to cnc and am using an Intel NUC for the computer and following Dr. D-flow's directions.

They state:

Open the network interfaces file by navigating to /etc/network/ and open the interfaces file via your file explorer or terminal. Add/change the text in this file to conform to the code below.
Other's on the forums say to do the same. The problem is that I can not edit the system files. They are read only and after extensive searching, I have not found directions on editing the files, almost as if no one has to unlock them.

The IP for the network card is set through the network GUI and the mesa 7I96S has jumpers set to 10.10.10.10 and I am able to ping the card, but with slow times.

I did not set a root password and only have a password on my user name, as instructed by: kcjengr.github.io/probe_basic/stable_quick_start_apt.html#

You would typically do this by launching the editor with sudo:

sudo mousepad /etc/network/interfaces

My interfaces file looks like this:

# interfaces(5) file used by ifup(8) and ifdown(8)
# Include files from /etc/network/interfaces.d:
source-directory /etc/network/interfaces.d
       auto eno1
       iface eno1 inet static
           address 10.10.10.100
           hardware-irq-coalesce-rx-usecs 0


Notes:
1. Your Ethernet device name may not be "eno1" (try "ip a" to discover your Ethernet device name)
2. If you configure the port in the interfaces file, you should disable any configuration done in the network manager GUI